The Groh Mansion was built in 1872 by Michael Groh as his residence. He was an important businessman in the area of lime-making in Ohio as he was instrumental in the supply of limestone and related products for the Midwest region. Michael Groh was also a significant builder who also built St. Peters Church in Cleveland.

The Groh Mansion is the solitary surviving residential building from this time of growth in Cleveland following the Civil War. It showcases the fine American architecture of the era at a Superior Avenue location which was, at the time, the home to some of the most fashionable residences in Cleveland.

The house was occupied between 1912 and 1918 by the city’s oldest and largest medical fraternity, Nu Sigma Nu. To accommodate the fraternity, the former attic was converted to a large meeting hall space, necessitating a new stairway and fire escape plus the elimination of the cornice such that larger windows could be installed in front.

From around 1944 till 1997, the building was used as a union hall for electrical workers.

Michael E. Chesler purchased the mansion in 1997 and the complete rehabilitation and redevelopment was completed in 1999.